Dr. Lawrence S. Feigenbaum, MD, FAAD

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Dr. Lawrence S. FeigenbaumDr. Feigenbaum grew up in Chesterfield, Missouri and is excited to provide medical, surgical, cosmetic, and hair dermatology services to the community he has always called home. A graduate of Parkway Central High School, Dr. Feigenbaum then continued his education at the University of Missouri where he graduated Summa Cum Laude with Highest Honors and Phi Beta Kappa distinction. He then went on to the University of Missouri School of Medicine where he continued to excel, graduating in the top of his class and being inducted into the prestigious Alpha Omega Alpha Society, the only national honor medical society in the world. He completed his residency training at Parkland Hospital/University of Texas-Southwestern in Dallas, Texas one of the top dermatology training programs in the country. During his senior year, he served as overall chief resident, scored in the 100th percentile on the national dermatology examination, and was awarded the Humanism & Professionalism Award as well as the Cognitive Excellence Award by faculty and peers.

Dr. Feigenbaum is committed to providing compassionate, patient-centered dermatologic care through communication and education. He has published numerous research articles, serves as an editorial reviewer for the dermatology journal Dermatitis, is a contributing author of dermatology board examination preparatory questions for the AAD, and holds membership in the American Academy of Dermatology, the American Society of Dermatologic Surgeons, the Missouri Dermatologic Society, and the St. Louis Dermatologic Society.

When he is not taking care of patients, Dr. Feigenbaum enjoys spending time with those he loves most – his fiancé, family, and close friends. He also enjoys watching Cardinals baseball, attending Mizzou basketball and football games, music production, exploring new restaurants, and traveling.

Research & Laboratory Experience

  • Migration of Facial Branchiomotor Neurons Using Mouse Model

Understanding the cellular and molecular mechanisms regulating neuronal migration and examining the behavioral consequences of defective migration

  • Genetic Underpinning of MDSC Function Using DC-HIL as a Marker

Studying molecular mechanisms through which myeloid cells (particularly, dendritic cells and macrophages) switch to the suppressor phenotype under the pathological conditions of melanoma and other cancers, using mouse models (transgenic and gene-disrupted mice) and human clinical samples

  • ADAM10, DC-HIL, and Melanoma

Elucidating ADAM10 function in ectodomain shedding and upregulation in melanoma metastasis, correlating soluble DC-HIL levels with melanoma metastatic potential, and seeking whether ADAM10 may be the candidate protease that mediates DC-HIL shedding.

Original Publications

  • Feigenbaum L, Skinner D, Golda N. Atypical cutaneous leiomyosarcoma with skip-lesion behavior. Dermatol Surg. 2013;39(4):660-2.
  • Feigenbaum L, Srivastava D, Nijhawan RI. Intraoperative retention sutures to facilitate closure. Journal of the American Academy of Dermatology. 2016; 75 (6): e229-e230.
  • Cao LY, Feigenbaum LS, Chung JS, Teshima T, et al. Myeloid-Derived Suppressor Cells in Psoriasis Are an Expanded Population Exhibiting Diverse T-Cell-Suppressor Mechanisms. J Invest Dermatol. 2016;136(9):1801-10
  • Feigenbaum L, Motaparthi K, Fradin M. A Serpiginous Plaque on the Trunk. JAMA Dermatol. 2016;152(7):831-2.
  • Feigenbaum, Lawrence. Cruz Jr., Ponciano. Acanthosis Nigricans. In: Mark G. Lebwohl MD, Warren R. Heymann MD, John Berth-Jones FRCP, Ian Coulson FRCP. Treatment of Skin Disease: Comprehensive Therapeutic Strategies. Philadelphia, PA: Saunders/Elsevier; 2016: 1-5.
  • Feigenbaum L, Scott BL, Moye MS, Nijhawan RI. Development of Basal Cell Carcinoma With Squamous Differentiation During Vismodegib Treatment. Dermatol Surg. June 2017.
  • Enos TH, Feigenbaum LS, Wickless HW. Brentuximab vedotin in CD30(+) primary cutaneous T-cell lymphomas: a review and analysis of existing data. Int J Dermatol. 2017;
  • Reconstruction of Near-Total Upper Lip Defect. Accepted. Dermatologic Surgery.

Oral Presentations

  • ADAM10 and DC-HIL: A New Beginning?
    University of Texas Southwestern, Department of Dermatology,
    Grand Rounds, June 2017
  • DC-HIL as a Marker for Melanoma Metastasis
    University of Texas Southwestern, Department of Dermatology,
    Grand Rounds, April 2016
  • Clinical Manifestations of Paraneoplastic Pemphigus
    Dallas Dermatology, November 2015
    Various Presentations of Erythema Multiforme
  • Dallas Dermatology, October 2015
    Dermatologic Manifestations of Systemic Disease
  • MacNeal Grand Rounds, April 2014
    Tuberculosis and Its Cutaneous Manifestations
  • University of California-Davis, Department of Dermatology, GrandRounds, August 2012
    Malignant Melanoma
  • American Society for Dermatologic Surgery Conference,
    Case Presentation, Atlanta, GA, October 2012
    Atypical Leiomyosarcoma