About St. Louis Dermatology

Specialists in St. Louis Dermatology & Cosmetic Medicine

We know you have many choices in St. Louis dermatology. As specialists in dermatology & cosmetic medicine, our physicians are board-certified dermatologists, led by our founder Dr. Lawrence Samuels.

From traditional clinical dermatology treatments to state-of-the-art aesthetic services, Specialists in Dermatology & Cosmetic Services has it all. Our practice combines the skills of leading St. Louis dermatologists with knowledgeable nurse practitioners to provide you with a complete range of clinical and cosmetic procedures.

We are committed to helping you experience the beauty that comes with healthy skin. Request a consultation online or call (314) 576-7343 to find out how you can achieve your best complexion.


Denise Apprill, RN, MSN, ANP-BC
Denise Apprill, RN, MSN, ANP-BC

Denise has been a Registered Nurse for 22 years, practicing dermatology, primary care and critical care. During that time, she completed advanced training in and performed many Botox, Juvederm XC and Juvaderm Voluma XC treatments, as well as other cosmetic procedures such as the treatment of spider and facial veins. Denise has a passion for reversing the aging process in her patients and providing them with more youthful, natural looking appearances. In addition to cosmetic treatments, she provides care to patients for common medical skin conditions. Denise has a BS in Biology from Indiana University, a Bachelors of Science in Nursing from St. Louis University, and a Masters of Science in Nursing from Maryville University and is Board Certified as an Adult Nurse Practitioner.

Peggy Nicolai, RN, MSN, FNP
Peggy Nicolai, RN, MSN, FNP

Peggy has been a Registered Nurse for over 38 years, with experience in nursing management, critical care and surgery. She is skilled at identifying and treating many skin disorders, and performing minor surgical excisions. In addition, Peggy is experienced at performing sclerotherapy for spider veins and Botox, Juvederm XC and Juvaderm Voluma XC treatments. Peggy’s friendly and helpful attitude assures her patients they are receiving the individual attention they need to resolve their skin issues. Peggy earned a Bachelors and a Masters of Science in Nursing from University of Phoenix and is Board Certified as a Family Nurse Practitioner.